Good eating quality: Practically attainable but still genetically unsolved

Chagas Disease: Still Many Unsolved Issues

Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi, as well as the receptors participating in parasite recognition by cells of the innate immune system, have been largely described. However, the main questions on the physiopathology of Chagas disease remain unanswered: "Why does the host immune system fail to provide sterile immunity?" and "Why d...

Congenital dyserythropoietic anemias: a still unsolved puzzle.

Dyserythropoiesis was the term used, for the first time by Crookston et al. in 19661 and later by Heimpel and Wendt,2 to indicate a congenital defect in erythropoiesis. However this term now refers to any alteration of the normal differentiation-proliferation pathway of the erythroid lineage. It incorporates both morphologic and kinetic aspects of erythropoiesis (erythroid lineage failure) and ...

Molecular Aspect of Good Eating Quality Formation in Japonica Rice

The composition of amylopectin is the determinant of rice eating quality under certain threshold of protein content and the ratio of amylose and amylopectin. In molecular biology level, the fine structure of amylopectin is determined by relative activities of starch branching enzyme (SBE), granule-bound starch synthase (GBSS), and soluble starch synthase (SSS) in rice grain under the same ADP-G...

Red blood cell antigen alloimmunization: Mysteries still unsolved

Article history: Received 10 June 2016 Accepted 10 June 2016 Available online 16 June 2016 pletion studies. They confirm the profound effect of storage on alloimmunization in this clear-cut model but also observe that NLRP3/ caspase-1 is not required for the effect (Gibb et al., 2016). While these data reject a relevant hypothesis that NLRP/caspase-1 is required (e.g. negative data), they do no...

The sylvatic cycle of Trypanosoma cruzi: a still unsolved puzzle.